acta satech Journal of the Life & Physical Sciences Babcock

Evaluation of insulin resistance and metabolic syndrome components in undergraduates of a Nigerian Private University
*Adejumo, E. N1., Adediji, I.O1., Olusanya, T.O2., Omodiale, P.E1. and Ojedele, M. T1.
1Department of Medical Laboratory Science, Babcock University, Ilishan Remo, Ogun State, Nigeria 2Department of Chemical Pathology, Babcock University Teaching Hospital, Ilishan Remo, Ogun State, Nigeria
September 2017

Background: The incidence of metabolic syndrome (MetS) and its components is increasing globally in all age groups. This study assessed insulin resistance and the components of metabolic syndrome among undergraduates of a Nigerian private University. Materials and Methods: Eighty undergraduates comprising of 38 males and 42 females, aged between 17-23 years were recruited for this study. Employing the National-Cholesterol-Education-Program—Third-Adult-TreatmentPanel (NCEP-ATPIII) and International Diabetes Federation (IDF) cut-off points for waist circumference (WC), the subjects were stratified into obese and non-obese groups. Anthropometric characteristics, blood pressure (BP), fasting plasma glucose (FPG), serum triglyceride, high density lipoprotein-cholesterol and insulin were determined by standard methods. Insulin resistance was calculated using the Homeostasis Model Assessment. Results: The most and least prevalent component of MetS observed were elevated blood pressure and elevated FPG respectively. By NCEP-ATPIII definition, 20% of obese subjects had 3 MetS components, however, by IDF definition, 22.4% of obese subjects had 4 MetS components. Among the non-obese subjects, 7.5% and 9.7% had 3 MetS components by NCEP-ATPIII and IDF definitions respectively. Insulin resistance had significant positive correlation with WC, body mass index, systolic BP and diastolic BP. Conclusion: Screening for metabolic risk factors is crucial in both obese and non-obese young adults as early detection can reduce the risk of developing cardiovascular disease later in life.
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