acta satech Journal of the Life & Physical Sciences Babcock

Antifungal activity of bark extract of Ficus vallis-choudae Delile-holl (Moraceae) and Detarium microcarpum Guill-Perr. (Caesalpinaceae)
*1Adekunle, A. A., 2Familoni, O. B. & 1Okoli, S. O.*
University of Lagos, 1Department of Botany & Microbiology, 2Department of Chemistry, Lagos, Nigeria
Received: 22 Nov., 2005 Revision accepted: 1st Nov., 2006

Ethanol and water crude extracts of Ficus vallis–choudae and Detarium microcarpum were investigated individually for antifungal activity by disc diffusion agar method. The phytochemical properties of the extracts were also assayed. The plant ethanol crude extracts had significant (P<0.01) antifungal activity with varying zones of inhibition on Aspergillus flavus, A. fumigatus, A. niger, Candida albicans, Microsporum audouinii, Trichoderma viride and Trichophyton mentagrophytes isolated from patients with skin diseases. The ethanol extracts were more active than the corresponding water extract. The ethanol extract of Ficus vallis–choudae caused the highest zone of inhibition (20.8±1.8mm) on Trichoderma viride. The crude extracts of the two plants contained anthocycanin, flavonoids, steroid and tannin.
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